On the Topic Manager page, click on "+ new challenge".
Click on "Quiz Challenge".
Click on either "Quiz Challenge (One Try Only)" or "Quiz Challenge (Repeatable)". See: What is the difference between "Single-Attempt Quiz Challenge" and "Multiple-Attempt Quiz Challenge"?
Write your question in the "Challenge Title" field. If you'd like, you can give your players more information/the context behind the question in the "Challenge Description" field.
Fill in the various quiz options your players will be able to choose from. Click "add another quiz option" to add more options, should you require them. There is no limit to the number of options you can provide your players with.
Check the circle next to the correct answer.
Now, scroll down and click 'save challenge'. Your Quiz Challenge is now ready.